Some principles for selecting high-quality medicinal plastic bottles

Because of the many specifications of medicinal plastic bottles, small dozens of milliliters, large thousands of milliliters, there is no color, there are transparent, colorful, various shapes, a wide range of categories. Faced with the brilliant market of plastic bottles, as a drug manufacturer, the following principles are mainly taken into consideration when selecting plastic bottles:



l, choose the plastic bottle main raw materials, additives formula: solid plastic bottles of product standards, respectively, provides the applicable main raw materials, and must comply with non-toxic, no odor and other requirements, due to the selection of the main raw materials, there are many , This requires the selection of the raw material's comprehensive performance. Generally, the tablet is made of high-density polyethylene, polypropylene bottles, and PET bottles can be used for transparency. For example, pharmaceuticals need to have higher barrier properties, and block light and opacity. PET bottles, better barrier performance PEN bottle. Liquid formulation drugs generally use polypropylene bottles or polyester bottles as the main raw material.



2, bottle body and cover sealing, water vapor permeability. Sealability and water vapor permeability are two important technical indicators of medicinal plastic bottles, and they play an important role in the stability of charge.



3, plastic bottle product quality standards. From the production plant's product quality standards can be analyzed and judged the pros and cons of product quality. Pharmaceutical plastic bottle companies should establish corporate standards that are stricter than national standards and industry standards.



4, quality assurance system. Auditing suppliers has become an essential part of purchasing plastic bottles. Through the audit, a comprehensive and correct assessment of the integrated level of the software and hardware facilities, technical equipment, and quality of the production plant can be made.



5, plastic bottle charge stability and compatibility. The use of plastic bottles, especially new drug selection of new plastic bottles (or new materials, new processes) should be carried out to test drug loading in order to investigate the stability of the charge and the compatibility between the plastic bottle and the drug. The penetration, dissolution, adsorption, chemical reaction, and denaturation of drugs and plastic bottles must be determined through scientific tests.